NSAIDs -anti-inflammatory action

NSAIDs are thought mainly to affect acute inflammatory processes through inhibiting the generation of thromboxane, prostacyclin, and the prostaglandins. They are not thought to dramatically affect the clinical progression of chronic inflammatory processes which are mediated by other mechanisms (many different cytokines are involved). However, chronic inflammation is often associated with intermittent episodes of acute inflammation and some degree of relief from the clinical signs associated with these episodes can be gained with the use of NSAIDs.

Chronic inflammation can sometimes lead on to cancer: NSAIDs have been shown to protect people from some of these cancers.

NSAIDs are not as effective as anti-inflammatory agents as corticosteroids. They do not delay healing in the way that steroids do.

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5 CNS index


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