Pain and analgesia
• pain signals are carried from the periphery to the brain by a number of routes
• pain signals are subject to modulation at several stages, particularly in the spinal cord (gating) which may increase or decrease the signal
• most analgesic drugs interfere with endogenous pain modulation systems
• pain changes over time so drug treatment of pain must change over time
• analgesic drugs are more effective if given before the pain starts
• good nursing is a useful adjunct to analgesic drugs

Pain and Analgesia

Pain: no completely satisfactory definition exists; that proposed by the International Association for the Study of Pain (for people) is the most widely accepted: "Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage." ie, pain consists of both a sensory component and an affective component. Some people also include a cognitive component, but I consider this a response to pain. (Other people deny that animals are capable of thinking.)
Analgesia = a lack of pain.
Nociception = the sensory component of pain. Since it is not possible to definitively prove that animals can feel pain, this term is sometimes misused (particularly by American physiologists) to mean pain in animals. A nociceptor is a nerve fibre used for pain signals.
Hyperalgesia and allodynia These are conditions which occur after pain perception has been altered by central or peripheral sensitisation. Hyperalgesia occurs when a stimulus which would have been painful before is now more painful; allodynia is when a previously innocuous stimulus (such as light touch) becomes painful. Sometimes these conditions persist after the injury has healed (hyperpathia).
Algogenic = something which produces pain.
Placebo = Latin “I will please” = inactive drug given to people who believe that it will do some good.
Nocebo = Latin “I will hurt” = inactive drug given to people who believe that it will cause problems. Most animals probably regard most veterinary drugs as nocebos.

Assessment of pain
Pain pathways
Gate theory
Response to injury
Analgesia

University of Edinburgh's Animal Pain web site